Polyethylene Glycol Coated Magnetic Nanoparticles: Hybrid Nanofluid Formulation, Properties and Drug Delivery Prospects

Magnetic nanoparticles (MNPs) are widely used materials for biomedical applications owing to their intriguing chemical, biological and magnetic properties. The evolution of MNP based (such as hyperthermia treatment drug delivery) could be advanced using nanofluids (MNFs) designed with a biocompatible surface coating strategy. This study presents the first report on loading/release capability MNF formulated methoxy polyethylene glycol (referred PEG) coated in aqueous (phosphate buffer) fluid. We have selected MNPs (NiFe2O4, CoFe2O4 Fe3O4) PEG formulation evaluated efficacy doxorubicin (DOX), an anticancer drug. presented detail loading capacity time-dependent cumulative release DOX from PEG-coated MNFs. Specifically, we three different MNFs compared variance DOX, through experimental results fitting into mathematical models. takes order > NiFe2O4 Fe3O4. Various models were suggested individual NFs. While non-Fickian diffusion (anomalous) model fits CoFe2O4, NF follows zero-order kinetics slow rate 1.33% per minute. On other hand, release. Besides, several thermophysical properties susceptibility concentrations been studied by dispersing base fluid at 300 K under ultrasonication. will set new paradigm view that can resolve problems related self-heating carriers during mild laser its thermal conducting